Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288016 | 0.86 | CCR1 (0.53) | CCR1 | |
| SCHEMBL13616997 | 0.86 | CCR1 (0.51) | CCR1 | |
| SCHEMBL13617524 | 0.86 | CCR1 (0.46) | CCR1TP53MDM2 | |
| SCHEMBL10287984 | 0.85 | CCR1 (0.51) | CCR1 | |
| SCHEMBL13617525 | 0.85 | CCR1 (0.44) | CCR1TP53 | |
| SCHEMBL13824493 | 0.85 | CCR1 (0.47) | CCR1TP53MDM2 | |
| SCHEMBL13824527 | 0.85 | CCR1 (0.42) | CCR1TP53MDM2 | |
| SCHEMBL12121895 | 0.84 | CCR1 (0.43) | CCR1TP53MDM2 | |
| SCHEMBL12121889 | 0.84 | CCR1 (0.44) | CCR1TP53MDM2 | |
| SCHEMBL12121888 | 0.84 | CCR1 (0.45) | CCR1TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541365-B2 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-06-02 | — | — | US | disclosed |