Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283872 | 0.88 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL2283866 | 0.88 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL2279796 | 0.85 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL2279790 | 0.85 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL13685251 | 0.84 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL2287074 | 0.84 | BACE1 (0.63) | BACE1CTSD | |
| SCHEMBL2287079 | 0.84 | BACE1 (0.63) | BACE1CTSD | |
| SCHEMBL7863649 | 0.83 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL2279267 | 0.83 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL2283319 | 0.83 | BACE1 (0.57) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796254-B2 | Methods for using carboxamide, sulfonamide and amine compounds | RIGEL PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |