Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.48 |
| ▸ | CTSD | P07339 | 10/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825459 | 0.90 | BACE1 (0.45) | BACE1CTSDRENBACE2 | |
| SCHEMBL13761021 | 0.88 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL2280141 | 0.87 | BACE1 (0.48) | BACE1CTSDRENBACE2 | |
| SCHEMBL2281753 | 0.87 | BACE1 (0.48) | BACE1CTSDRENBACE2 | |
| SCHEMBL2280146 | 0.87 | BACE1 (0.48) | BACE1CTSDRENBACE2 | |
| SCHEMBL13825469 | 0.86 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL13760888 | 0.85 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL13825351 | 0.83 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL7874719 | 0.81 | BACE1 (0.52) | BACE1CTSDRENBACE2 | |
| SCHEMBL2285136 | 0.81 | BACE1 (0.60) | BACE1CTSDRENBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |