Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825384 | 0.93 | BACE1 (0.55) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL13825392 | 0.90 | BACE1 (0.60) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL13825328 | 0.90 | BACE1 (0.52) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL13825508 | 0.89 | BACE1 (0.63) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL13825360 | 0.87 | BACE1 (0.49) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL2283268 | 0.85 | BACE1 (0.63) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL2283262 | 0.85 | BACE1 (0.63) | BACE1KCNH2APPBACE2CTSD | |
| Formic Acid SCHEMBL2286086 | 0.81 | BACE1 (0.60) | BACE1KCNH2APPBACE2CTSD | |
| SCHEMBL13825385 | 0.80 | BACE1 (0.54) | BACE1KCNH2BACE2CTSD | |
| SCHEMBL13825358 | 0.80 | BACE1 (0.49) | BACE1KCNH2BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |