Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485245 | 0.84 | PDE10A (0.66) | PDE10A | |
| SCHEMBL2487048 | 0.83 | PDE10A (0.66) | PDE10A | |
| SCHEMBL2485078 | 0.82 | PDE10A (0.67) | PDE10A | |
| SCHEMBL2486491 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2483477 | 0.79 | PDE10A (0.66) | PDE10A | |
| SCHEMBL7903756 | 0.79 | — | — | |
| SCHEMBL3466968 | 0.79 | — | — | |
| SCHEMBL2485197 | 0.78 | — | — | |
| SCHEMBL2487556 | 0.78 | — | — | |
| SCHEMBL13685557 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376455-B1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC (US) | 2012-11-14 | — | — | EP | disclosed |