Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200660 | 1.00 | MGAM (0.40) | MGAMCA1CA2GAASI | |
| SCHEMBL16602936 | 1.00 | MGAM (0.40) | MGAMCA1CA2GAASI | |
| SCHEMBL10100000 | 1.00 | MGAM (0.40) | MGAMCA1CA2GAASI | |
| SCHEMBL10063791 | 1.00 | MGAM (0.40) | MGAMCA1CA2GAASI | |
| SCHEMBL14403895 | 0.82 | MGAM (0.39) | MGAMCA1CA2GAASI | |
| SCHEMBL14232901 | 0.82 | MGAM (0.39) | MGAMCA1CA2GAASI | |
| SCHEMBL12510719 | 0.82 | MGAM (0.39) | MGAMCA1CA2GAASI | |
| SCHEMBL13300885 | 0.80 | — | — | |
| SCHEMBL13321423 | 0.80 | — | — | |
| SCHEMBL14403629 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2522663-A1 | Intermediates for the preparation of halichondrin B | Eisai R&D Management Co., Ltd. (JP) | 2012-11-14 | — | — | EP | disclosed |