Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.82 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707519 | 1.00 | AR (0.82) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL12267221 | 1.00 | AR (0.82) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL14707518 | 1.00 | AR (0.82) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL14707517 | 1.00 | AR (0.82) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL14707520 | 1.00 | AR (0.82) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL12267198 | 0.92 | AR (0.76) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL12267194 | 0.90 | AR (1.00) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL12267202 | 0.90 | AR (0.74) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL15257224 | 0.90 | AR (1.00) | ARHTTHIF1AKMT2AKDM4E | |
| SCHEMBL13736034 | 0.90 | AR (1.00) | ARHTTHIF1AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012145328-A1 | DIBENZYLPHENYL COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-10-26 | — | — | WO | disclosed |