Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.48 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826483 | 0.97 | ESR1 (0.59) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL22461713 | 0.88 | ESR1 (0.65) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL13299511 | 0.84 | ESR1 (0.54) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL13299513 | 0.83 | ESR1 (0.56) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL14160911 | 0.83 | ESR1 (0.73) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL26344978 | 0.81 | ESR1 (0.51) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL13826714 | 0.81 | ESR1 (0.48) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL16692234 | 0.81 | ESR2 (0.71) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL10041513 | 0.81 | ESR2 (0.71) | ESR1ESR2KDM4EHSD17B10HTT | |
| SCHEMBL13299593 | 0.81 | ESR1 (0.54) | ESR1ESR2KDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9735371-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-9735371-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20170179399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
| US-20170179399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
| EP-2699641-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20140231715-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2014-08-21 | — | — | US | disclosed |
| US-20140231715-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2014-08-21 | — | — | US | disclosed |
| WO-2012143079-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170179399-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, CYP1B1, CYP2C9 | ESR1 40/4885ESR2 275/4885KDM4E 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.