Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497372 | 0.92 | MEN1 (0.50) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL24635373 | 0.72 | HTR2A (0.67) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL30876125 | 0.72 | HTR2A (0.67) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL30027791 | 0.72 | HTR2A (0.67) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL30027614 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL7517139 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL30876136 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL24635619 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL24635620 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL30876124 | 0.71 | HSD17B10 (0.86) | HSD17B10CYP2D6MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | ENZON PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | AURKA, DSTYK, TYR | HSD17B10 4271/4885CYP2D6 3165/4885MEN1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.