Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827214 | 1.00 | AR (0.45) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13827280 | 0.95 | AR (0.53) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13827215 | 0.95 | AR (0.53) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13827570 | 0.94 | AR (0.40) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13827150 | 0.92 | AR (0.42) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13733373 | 0.90 | AR (0.41) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13733377 | 0.90 | AR (0.41) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL14546243 | 0.88 | MAPT (0.45) | SMN1; SMN2MAPTHTTLMNAKMT2A | |
| SCHEMBL13827400 | 0.87 | PLA2G4B (0.40) | ARSMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13827566 | 0.87 | AR (0.39) | ARSMN1; SMN2MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012145330-A1 | FLUORENE-9-BISPHENOL COMPOUNDS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-10-26 | — | — | WO | disclosed |