Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807501 | 0.91 | DRD4 (0.57) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1807499 | 0.91 | DRD4 (0.57) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12655639 | 0.91 | CCR3 (0.65) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1809649 | 0.90 | DRD4 (0.56) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1809651 | 0.90 | DRD4 (0.56) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1809601 | 0.83 | DRD4 (0.54) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1809602 | 0.83 | DRD4 (0.54) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4021624 | 0.83 | CCR3 (0.59) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4474137 | 0.82 | DRD4 (0.55) | DRD4CCR3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6265631 | 0.82 | DRD4 (0.55) | DRD4CCR3CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801108-B1 | MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-11-14 | — | — | EP | disclosed |