Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632737 | 0.94 | TSHR (0.56) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL12632812 | 0.94 | TSHR (0.56) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL12632480 | 0.90 | TSHR (0.51) | TSHRCYP3A4CYP1A2NPC1SAE1 | |
| SCHEMBL19214039 | 0.83 | CYP3A4 (0.43) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL13828462 | 0.83 | CYP3A4 (0.43) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL13828465 | 0.83 | CYP3A4 (0.43) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL17525632 | 0.81 | TSHR (0.53) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL13828464 | 0.80 | SAE1 (0.43) | TSHRCYP3A4CYP1A2NPC1SAE1 | |
| SCHEMBL13158577 | 0.80 | TSHR (0.51) | TSHRCYP3A4CYP1A2SAE1UBA2 | |
| SCHEMBL12604117 | 0.79 | TSHR (0.65) | TSHRCYP3A4CYP1A2NPC1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289619-A1 | Flame Retardant Polyurethane Foams Containing Biuret Linkages | DOW GLOBAL TECHNOLOGIES LLC. | 2012-11-15 | — | — | US | disclosed |