Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 7/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630006 | 1.00 | KCNQ1 (0.53) | KCNQ1HCRTR1HCRTR2POLBCTSS | |
| SCHEMBL629908 | 0.90 | KCNQ1 (0.46) | KCNQ1HCRTR1HCRTR2POLBCTSS | |
| SCHEMBL629838 | 0.85 | KCNQ1 (0.62) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL5173103 | 0.85 | KCNQ1 (0.62) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL629837 | 0.85 | KCNQ1 (0.62) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL630219 | 0.84 | KCNQ1 (0.58) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL1380661 | 0.82 | KCNQ1 (0.56) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL630034 | 0.82 | KCNQ1 (0.56) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL630184 | 0.81 | KCNQ1 (0.58) | KCNQ1HCRTR1HCRTR2POLBITGB1 | |
| SCHEMBL630183 | 0.81 | KCNQ1 (0.58) | KCNQ1HCRTR1HCRTR2POLBITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4812758-B2 | — | — | 2011-11-09 | — | — | JP | claimed |