Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 10/20 | 0.37 |
| ▸ | MAOA | P21397 | 7/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730905 | 1.00 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL19730903 | 1.00 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL13562897 | 1.00 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL19730904 | 0.81 | HTR2A (0.52) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL13893724 | 0.81 | HTR2A (0.52) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL24868374 | 0.74 | HTR2C (0.46) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL8294601 | 0.74 | HTR2A (0.66) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL9381870 | 0.74 | HTR2B (0.46) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL9381875 | 0.74 | HTR2B (0.46) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL4436188 | 0.74 | HTR2C (1.00) | HTR2AHTR2CHTR2BMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2522648-B1 | PROCESS FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | CENTRAL GLASS CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-8729320-B2 | Method for producing difluorocyclopropane compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2522648-A1 | PROCESS FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | Central Glass Company, Limited (JP) | 2012-11-14 | — | — | EP | disclosed |