Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727797 | 0.85 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6834987 | 0.80 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9148240 | 0.79 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Trimethylammonium SCHEMBL8522437 | 0.79 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10349929 | 0.79 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9159437 | 0.79 | HCAR2 (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5890320 | 0.79 | HCAR2 (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9159446 | 0.79 | HCAR2 (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28802538 | 0.78 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9466873 | 0.78 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120296029-A1 | FLUORINE-CONTAINING MULTIFUNCTIONAL MICROSPHERES AND USES THEREOF | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-11-22 | — | — | US | disclosed |