Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | EPHA5 | P54756 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417014 | 0.97 | MAPK14 (0.47) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1416992 | 0.95 | MAPK14 (0.49) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1417099 | 0.87 | MAPK14 (0.50) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1417219 | 0.85 | HPGD (0.54) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1417180 | 0.84 | MAPK14 (0.56) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1385955 | 0.84 | MAPK14 (0.51) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1382836 | 0.84 | MAPK14 (0.48) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1386374 | 0.83 | MAPK14 (0.60) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1417233 | 0.83 | MAPK14 (0.50) | MAPK14MAPK11GAKLCKCYP3A4 | |
| SCHEMBL1386397 | 0.83 | MAPK14 (0.54) | MAPK14MAPK11GAKLCKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4838121-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| JP-2007521278-A | — | — | 2007-08-02 | — | — | JP | claimed |
| EP-1641764-A1 | 5-MEMBERED HETEROCYCLE-BASED P38 KINASE INHIBITORS | Novartis AG (CH) | 2006-04-05 | — | — | EP | claimed |
| WO-2005009973-A1 | 5-MEMBERED HETEROCYCLE-BASED P38 KINASE INHIBITORS | NOVARTIS AG (CH) | 2005-02-03 | — | — | WO | claimed |