Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.41 |
| ▸ | IL2 | P60568 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727379 | 0.76 | ABL1 (0.43) | ABL1IL2ABCB1 | |
| SCHEMBL13729020 | 0.74 | ABL1 (0.42) | ABL1IL2ABCB1 | |
| SCHEMBL13727631 | 0.74 | ABL1 (0.42) | ABL1IL2ABCB1 | |
| SCHEMBL15806462 | 0.71 | ABL1 (0.44) | ABL1IL2ABCB1 | |
| SCHEMBL13728036 | 0.71 | ABL1 (0.44) | ABL1IL2ABCB1 | |
| SCHEMBL13729007 | 0.71 | ABL1 (0.45) | ABL1IL2ABCB1 | |
| SCHEMBL13838426 | 0.70 | ABL1 (0.45) | ABL1ABCB1 | |
| SCHEMBL13838359 | 0.70 | NPC1 (0.43) | ABL1ABCB1 | |
| SCHEMBL13727823 | 0.70 | GRM5 (0.44) | ABL1ABCB1 | |
| SCHEMBL13727725 | 0.69 | ABL1 (0.42) | ABL1IL2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151355-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-11-08 | — | — | WO | disclosed |