Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596591 | 1.00 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL15184686 | 1.00 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL420093 | 1.00 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL15769664 | 0.88 | — | — | |
| SCHEMBL10768301 | 0.84 | TP53 (0.39) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL13839690 | 0.84 | TP53 (0.45) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL3886854 | 0.84 | TP53 (0.45) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL13839704 | 0.84 | TP53 (0.45) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL15013766 | 0.79 | TP53 (0.54) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL19276892 | 0.78 | UGT2B7 (0.33) | TP53UGT2B7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534905-B2 | Reagents for asymmetric allylation, aldol, and tandem aldol and allyation reactions | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534905-B2 | Reagents for asymmetric allylation, aldol, and tandem aldol and allyation reactions | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-19 | — | — | US | disclosed |