SCHEMBL13840484

SCHEMBL13840484

Cc1ccc(CC2CC(c3ccc(Cl)cc3)=NO2)cc1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2919362 0.89 NPC1 (0.55) NPC1RAB9A
SCHEMBL2914695 0.86 NPC1 (0.53) NPC1RAB9A
SCHEMBL2920586 0.86 NPC1 (0.52) NPC1RAB9A
SCHEMBL2918925 0.86
SCHEMBL2920465 0.85 MIF (0.58)
SCHEMBL12294594 0.81 NPC1 (0.65) NPC1RAB9A
SCHEMBL2915830 0.80 KMT2A (0.53) NPC1RAB9A
SCHEMBL14183685 0.79 NPC1 (0.52) NPC1RAB9A
SCHEMBL8243017 0.79 MIF (0.52) NPC1RAB9A
SCHEMBL2921731 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009066009-A1 NOVEL 4,5-DIHYDROISOXAZOLES WITH ESTROGENIC ACTIVITY PULKKINEN JUHA (FI) 2009-05-28 WO disclosed