Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841151 | 1.00 | HPGD (0.51) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13841148 | 0.94 | HPGD (0.54) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839550 | 0.90 | NPC1 (0.54) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839480 | 0.89 | MAPT (0.49) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839541 | 0.89 | MAPT (0.49) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839558 | 0.89 | HPGD (0.51) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839517 | 0.89 | NPC1 (0.55) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839526 | 0.88 | HPGD (0.50) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839500 | 0.86 | NPC1 (0.49) | HPGDCYP1A2CYP2C19LMNACYP3A4 | |
| SCHEMBL13839518 | 0.86 | NPC1 (0.51) | HPGDCYP1A2CYP2C19LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |