Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FARS2 | O95363 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104431 | 1.00 | FARS2 (0.57) | FARS2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL13847077 | 0.95 | FARS2 (0.50) | FARS2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL13119897 | 0.95 | FARS2 (0.50) | FARS2RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL13104414 | 0.92 | FARS2 (0.60) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL13104427 | 0.88 | FARS2 (0.74) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL13104371 | 0.88 | FARS2 (0.74) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL14565750 | 0.88 | FARS2 (0.57) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL13104394 | 0.81 | FARS2 (0.64) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL13119892 | 0.81 | FARS2 (0.53) | FARS2RAB9ANPC1MAPTPKM | |
| SCHEMBL13104361 | 0.80 | FARS2 (0.69) | FARS2RAB9ANPC1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528167-B2 | Inhibitors of papilloma virus | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2009-05-05 | — | — | US | disclosed |