Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980765 | 0.74 | MRGPRX1 (0.64) | HSD17B10MKNK2HPGDATMMRGPRX1 | |
| SCHEMBL3977843 | 0.68 | HSD17B10 (0.48) | HSD17B10MKNK2HPGDATMMKNK1 | |
| SCHEMBL2368112 | 0.67 | HPGD (0.57) | HSD17B10MKNK2HPGDATMMKNK1 | |
| SCHEMBL4365183 | 0.66 | MRGPRX1 (0.51) | HSD17B10MKNK2HPGDATMMRGPRX1 | |
| SCHEMBL4369869 | 0.65 | HSD17B10 (0.52) | HSD17B10MKNK2HPGDATMMKNK1 | |
| SCHEMBL3979886 | 0.65 | MRGPRX1 (0.49) | HSD17B10MKNK2HPGDMRGPRX1MKNK1 | |
| SCHEMBL23630827 | 0.65 | HSD17B10 (1.00) | HSD17B10HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL3977837 | 0.64 | MKNK2 (0.52) | HSD17B10MKNK2HPGDATM | |
| SCHEMBL2368331 | 0.62 | MKNK2 (0.82) | MKNK2 | |
| SCHEMBL15426163 | 0.62 | FGFR1 (0.67) | MKNK2MKNK1LMNAFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |