Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526785 | 0.90 | F10 (0.48) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4390586 | 0.87 | F10 (0.44) | F10 | |
| SCHEMBL4390583 | 0.87 | F10 (0.44) | F10 | |
| SCHEMBL1652716 | 0.82 | F10 (0.70) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1652862 | 0.82 | F10 (0.70) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1652714 | 0.82 | F10 (0.70) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1386589 | 0.78 | F10 (0.71) | F10 | |
| SCHEMBL4391897 | 0.78 | F10 (0.41) | F10 | |
| SCHEMBL4397921 | 0.76 | F10 (0.44) | F10CYP2C9 | |
| SCHEMBL4397916 | 0.76 | F10 (0.44) | F10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |