SCHEMBL13845255

SCHEMBL13845255

CC(C)(C)OC(=O)/C=C\c1ccc2cc(OC(=O)OC(C)(C)C)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.48
ESR1 P03372 1/20 0.46
KMT2A Q03164 3/20 0.45
MAPT P10636 3/20 0.45
MEN1 O00255 1/20 0.45
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TRPV1 Q8NER1 1/20 0.43
CA2 P00918 1/20 0.42
HTT P42858 2/20 0.42
JAK2 O60674 1/20 0.42
GAA P10253 1/20 0.42
MAOB P27338 1/20 0.40
PPARA Q07869 1/20 0.40
NR1H4 Q96RI1 3/20 0.39
TTR P02766 1/20 0.39
APP P05067 1/20 0.39
GLA P06280 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4054087 1.00 ELANE (0.48) ELANEESR1KMT2AMAPTMEN1
SCHEMBL4054092 1.00 ELANE (0.48) ELANEESR1KMT2AMAPTMEN1
SCHEMBL4060081 0.90 ESR1 (0.49) ESR1KMT2AMAPTMEN1CA2
SCHEMBL4060087 0.90 ESR1 (0.49) ESR1KMT2AMAPTMEN1CA2
SCHEMBL1399888 0.86 ESR1 (0.59) ESR1KMT2AMAPTMEN1MAOB
SCHEMBL4548370 0.86 ESR1 (0.59) ESR1KMT2AMAPTMEN1MAOB
SCHEMBL13845249 0.84 ELANE (0.53) ELANEESR1KMT2AMAPTMEN1
SCHEMBL4065940 0.84 ELANE (0.53) ELANEESR1KMT2AMAPTMEN1
SCHEMBL13845250 0.84 ELANE (0.53) ELANEESR1KMT2AMAPTMEN1
SCHEMBL5396213 0.84 PPARA (0.51) KMT2AMAPTMEN1PPARAAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed