Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 6/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758017 | 0.91 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL9885645 | 0.91 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL764555 | 0.91 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL31717031 | 0.86 | CHRM2 (0.50) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL16876681 | 0.86 | CHRM2 (0.50) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL30397638 | 0.86 | CHRM2 (0.50) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL14668817 | 0.85 | CHRM2 (0.44) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL21456554 | 0.84 | CHRM2 (0.54) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL14047316 | 0.81 | NR1H2 (0.51) | CHRM2CHRM1CHRM3CETPNR1H2 | |
| SCHEMBL24503254 | 0.80 | NR1H2 (0.40) | CHRM2CHRM1CHRM3CETPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-1807423-B1 | QUINOLINONE-CARBOXAMIDE COMPOUNDS | THERAVANCE INC (US) | 2009-05-20 | — | — | EP | disclosed |