Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981939 | 0.87 | MEN1 (0.67) | MAPTMEN1KMT2AARSMN1; SMN2 | |
| SCHEMBL1883726 | 0.87 | MEN1 (0.64) | MAPTMEN1KMT2AARSMN1; SMN2 | |
| SCHEMBL16396158 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2AARALDH1A1 | |
| SCHEMBL15698887 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17135408 | 0.78 | MEN1 (0.81) | MAPTMEN1KMT2ALMNAHIF1A | |
| SCHEMBL26605120 | 0.77 | MAPT (0.51) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15697526 | 0.74 | MAPT (0.82) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2845868 | 0.74 | MEN1 (0.73) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL1888015 | 0.74 | MAPT (0.77) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18264030 | 0.73 | PTPN2 (0.49) | MAPTMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | disclosed |