Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 17/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 17/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746330 | 0.86 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1 | |
| SCHEMBL13845681 | 0.85 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1ADORA3ADORA2AADORA1 | |
| SCHEMBL3518947 | 0.83 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 | |
| SCHEMBL13845736 | 0.82 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL13845680 | 0.80 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1 | |
| SCHEMBL3533190 | 0.75 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL3743309 | 0.72 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1 | |
| SCHEMBL3522271 | 0.71 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1 | |
| SCHEMBL3757684 | 0.71 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3522061 | 0.71 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |