Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730104 | 0.85 | OPRL1 (0.58) | OPRL1C5AR1OPRM1OPRK1EGLN1 | |
| SCHEMBL16618821 | 0.81 | CNR1 (0.54) | OPRL1DRD4OPRM1OPRK1EGLN1 | |
| SCHEMBL2302362 | 0.80 | CHRM1 (0.52) | OPRL1OPRM1OPRK1EGLN1CNR1 | |
| SCHEMBL17083919 | 0.78 | CNR1 (0.48) | OPRL1OPRM1OPRK1CNR1GPR55 | |
| SCHEMBL11472449 | 0.78 | EGLN1 (0.63) | OPRL1DRD4C5AR1OPRM1OPRK1 | |
| SCHEMBL30666913 | 0.76 | CNR1 (0.49) | OPRL1DRD4OPRM1OPRK1EGLN1 | |
| SCHEMBL2298738 | 0.75 | CNR1 (0.48) | OPRL1DRD4OPRM1OPRK1EGLN1 | |
| SCHEMBL17083918 | 0.72 | CNR1 (0.50) | OPRL1DRD4OPRM1OPRK1CNR1 | |
| SCHEMBL10253956 | 0.71 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL16618696 | 0.70 | OPRL1 (0.51) | OPRL1OPRM1OPRK1EGLN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061676-A2 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |