Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 13/20 | 0.76 |
| ▸ | PSMB8 | P28062 | 12/20 | 0.76 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661923 | 1.00 | PSMB5 (0.76) | PSMB5PSMB8CTRB1MRGPRX4MEP1A | |
| SCHEMBL13846025 | 0.91 | PSMB5 (0.61) | PSMB5PSMB8CTRB1 | |
| SCHEMBL3658451 | 0.91 | PSMB5 (0.61) | PSMB5PSMB8CTRB1 | |
| SCHEMBL13846042 | 0.90 | PSMB5 (0.68) | PSMB5PSMB8CTRB1 | |
| SCHEMBL3659451 | 0.90 | PSMB5 (0.68) | PSMB5PSMB8CTRB1 | |
| SCHEMBL3771117 | 0.89 | PSMB5 (0.64) | PSMB5PSMB8CTRB1 | |
| SCHEMBL13846028 | 0.89 | PSMB5 (0.64) | PSMB5PSMB8CTRB1 | |
| SCHEMBL13062124 | 0.88 | PSMB5 (0.62) | PSMB5PSMB8CTRB1MRGPRX4CNR2 | |
| SCHEMBL3660792 | 0.88 | PSMB5 (0.62) | PSMB5PSMB8CTRB1MRGPRX4CNR2 | |
| SCHEMBL3662229 | 0.86 | PSMB5 (0.61) | PSMB5PSMB8MRGPRX4MEP1AMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064413-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |