Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 14/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662229 | 1.00 | PSMB5 (0.61) | PSMB5PSMB8TP53PKMNFKB1 | |
| SCHEMBL3653865 | 0.91 | PSMB5 (0.60) | PSMB5PSMB8TP53PKMNFKB1 | |
| SCHEMBL13846026 | 0.91 | PSMB5 (0.60) | PSMB5PSMB8TP53PKMNFKB1 | |
| SCHEMBL13846042 | 0.88 | PSMB5 (0.68) | PSMB5PSMB8 | |
| SCHEMBL3659451 | 0.88 | PSMB5 (0.68) | PSMB5PSMB8 | |
| SCHEMBL13845972 | 0.88 | PSMB5 (0.55) | PSMB5PSMB8PKMSMN1; SMN2MRGPRX4 | |
| SCHEMBL3773145 | 0.88 | PSMB5 (0.55) | PSMB5PSMB8PKMSMN1; SMN2MRGPRX4 | |
| SCHEMBL13846028 | 0.87 | PSMB5 (0.64) | PSMB5PSMB8 | |
| SCHEMBL3771117 | 0.87 | PSMB5 (0.64) | PSMB5PSMB8 | |
| SCHEMBL3658382 | 0.87 | PSMB5 (0.51) | PSMB5PSMB8TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064413-A1 | BETA-LACTAMASE INHIBITORS | PROTEZ PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |