Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 12/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926337 | 0.91 | LCK (0.39) | LCKMAPT | |
| SCHEMBL2910691 | 0.90 | LCK (0.40) | LCKMAPTSCN9AKMT2A | |
| SCHEMBL2915053 | 0.87 | MAPT (0.41) | LCKMAPTKMT2A | |
| SCHEMBL13846345 | 0.85 | LCK (0.44) | LCKPARP14KMT2A | |
| SCHEMBL8077962 | 0.83 | CFTR (0.40) | LCKMAPTKMT2A | |
| SCHEMBL2920262 | 0.81 | LCK (0.44) | LCKMAPTPARP14 | |
| SCHEMBL13846351 | 0.80 | LCK (0.43) | LCKMAPT | |
| SCHEMBL13846349 | 0.79 | LCK (0.42) | LCKMAPT | |
| SCHEMBL2940199 | 0.73 | CFTR (0.38) | LCKMAPTKMT2A | |
| SCHEMBL2940202 | 0.71 | CFTR (0.38) | LCKMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067604-A1 | SUBSTITUTED BENZOAZOLE PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009067618-A1 | SUBSTITUTED BENZOAZOLE PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |