Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920743 | 0.86 | LCK (0.49) | LCKDYRK1ADUSP3GSK3B | |
| SCHEMBL13846349 | 0.82 | LCK (0.42) | LCKDYRK1ADUSP3 | |
| SCHEMBL13847104 | 0.81 | LCK (0.50) | LCK | |
| SCHEMBL2920867 | 0.78 | LCK (0.43) | LCKDYRK1ADUSP3 | |
| SCHEMBL2920980 | 0.75 | MAPT (0.40) | LCKDYRK1ADUSP3 | |
| SCHEMBL13846345 | 0.74 | LCK (0.44) | LCK | |
| SCHEMBL13846520 | 0.74 | LCK (0.58) | LCK | |
| SCHEMBL13846353 | 0.73 | LCK (0.48) | LCK | |
| SCHEMBL19630817 | 0.72 | LCK (0.54) | LCKDYRK1A | |
| SCHEMBL2274858 | 0.71 | LCK (0.61) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067604-A1 | SUBSTITUTED BENZOAZOLE PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009067618-A1 | SUBSTITUTED BENZOAZOLE PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |