Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 10/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109809 | 0.88 | PPARD (0.48) | PPARDPPARAPPARGKIF11TRPV3 | |
| SCHEMBL4119348 | 0.85 | SIRT2 (0.48) | PPARDPPARAPPARGKIF11TRPV3 | |
| SCHEMBL12151278 | 0.81 | PPARD (0.46) | PPARDPPARAPPARGKIF11SIRT2 | |
| SCHEMBL13334280 | 0.81 | PPARD (0.46) | PPARDPPARAPPARGKIF11SIRT2 | |
| SCHEMBL12151189 | 0.81 | PPARD (0.48) | PPARDPPARAPPARGKIF11TRPV3 | |
| SCHEMBL12151052 | 0.78 | PPARD (0.51) | PPARDPPARAPPARGKIF11TRPV3 | |
| SCHEMBL23862105 | 0.74 | PPARD (0.51) | PPARDPPARAPPARGTRPV3 | |
| SCHEMBL4101432 | 0.74 | PPARA (0.64) | PPARDPPARAPPARGKIF11 | |
| SCHEMBL4114514 | 0.73 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL4190251 | 0.73 | HDAC1 (0.60) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131489-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | KUO GEE-HONG | 2009-05-21 | — | — | US | disclosed |
| US-20090131489-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | KUO GEE-HONG | 2009-05-21 | — | — | US | disclosed |
| US-7498351-B2 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-03 | — | — | US | disclosed |
| US-7498351-B2 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131489-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.