SCHEMBL1384869

SCHEMBL1384869

COCC1CN(C(=O)COc2ccc(Cl)s2)C(COC)C(=O)N1Cc1ccc2c(N)ncnc2c1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 12/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1653034 0.96 F10 (0.40) F10
SCHEMBL4395010 0.96 F10 (0.40) F10
SCHEMBL1652492 0.93 F10 (0.41) F10
SCHEMBL4392691 0.93 F10 (0.41) F10
SCHEMBL1384586 0.87 F10 (0.43) F10
SCHEMBL1303767 0.87 F10 (0.43) F10
SCHEMBL1384588 0.87 F10 (0.43) F10
SCHEMBL1386506 0.86 F10 (0.47) F10
SCHEMBL1385481 0.86 F10 (0.47) F10
SCHEMBL1385482 0.86 F10 (0.47) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed
US-7612075-B2 Substituted oxoazaheterocyclyl compounds AVENTIS PHARMACEUTICALS INC. (US) 2009-11-03 US disclosed