Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301296 | 0.94 | BRAF (0.43) | BRAFMAPK14 | |
| SCHEMBL13848679 | 0.94 | BRAF (0.43) | BRAFMAPK14 | |
| SCHEMBL13848689 | 0.92 | BRAF (0.47) | BRAFMAPK14 | |
| SCHEMBL13887583 | 0.92 | BRAF (0.45) | BRAFMAPK14 | |
| SCHEMBL13848855 | 0.92 | BRAF (0.43) | BRAF | |
| SCHEMBL13887628 | 0.90 | BRAF (0.43) | BRAFMAPK14 | |
| SCHEMBL13848981 | 0.90 | BRAF (0.43) | BRAFMAPK14 | |
| SCHEMBL13848681 | 0.89 | BRAF (0.50) | BRAFMAPK14 | |
| SCHEMBL13848850 | 0.89 | BRAF (0.39) | BRAFMAPK14 | |
| SCHEMBL13887686 | 0.89 | MAPK14 (0.38) | BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725544-B1 | 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1887003-A1 | 3-[4-HETEROCYCLYL -1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7214802-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214802-B2 | Anti-cytokine heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-05-08 | — | — | US | disclosed |