Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653352 | 0.92 | F10 (0.53) | F10MAP4K4DPP4 | |
| SCHEMBL1654455 | 0.85 | F10 (0.58) | F10MAP4K4 | |
| SCHEMBL1651375 | 0.82 | F10 (0.54) | F10DPP4 | |
| SCHEMBL1385117 | 0.82 | F10 (0.43) | F10 | |
| SCHEMBL1385120 | 0.82 | F10 (0.43) | F10 | |
| SCHEMBL1652171 | 0.82 | F10 (0.52) | F10 | |
| SCHEMBL1387093 | 0.82 | F10 (0.42) | F10 | |
| SCHEMBL1387090 | 0.82 | F10 (0.42) | F10 | |
| SCHEMBL1654561 | 0.81 | F10 (0.48) | F10MAP4K4DPP4AKT1 | |
| SCHEMBL1654563 | 0.81 | F10 (0.48) | F10MAP4K4DPP4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |
| CN-1420882-A | Substd. oxoazaheterocyclyl compounds | AVENTIS PHARM PROD INC (US) | 2003-05-28 | — | — | CN | disclosed |