SCHEMBL1385168

SCHEMBL1385168

Cc1cncc2cc(CN3CCN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3=O)[nH]c12

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.75
F2 P00734 2/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1384898 0.86 F10 (1.00) F10F2
SCHEMBL1652677 0.84 F10 (1.00) F10F2
Trifluoroacetic Acid SCHEMBL4397265 0.81 F10 (0.88) F10F2
SCHEMBL1652800 0.79 F10 (0.74) F10F2
SCHEMBL1653109 0.79 F10 (0.80) F10F2
SCHEMBL1654339 0.79 F10 (0.73) F10F2
SCHEMBL1651631 0.78 F10 (0.72) F10F2
SCHEMBL1652902 0.78 F10 (0.75) F10F2
SCHEMBL1385460 0.78 F10 (0.63) F10F2
SCHEMBL1654478 0.78 F10 (0.75) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed