SCHEMBL1385366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1383814	0.89	KCNA5 (0.62)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL13380069	0.87	KCNA5 (0.60)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL1385303	0.86	KCNA5 (0.59)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL1386391	0.85	KCNA5 (0.67)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL3122261	0.84	KCNA5 (0.57)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL3124078	0.84	KCNA5 (0.54)	KCNA5KCNH2SQORALDH1A1MAPT
	SCHEMBL3120734	0.83	KCNA5 (0.72)	KCNA5KCNH2MAT2ACYP1A2CYP3A4
	SCHEMBL1381903	0.83	KCNA5 (1.00)	KCNA5KCNH2MAT2ACYP1A2ALDH1A1
	SCHEMBL1382221	0.83	KCNA5 (1.00)	KCNA5KCNH2MAT2ACYP1A2ALDH1A1
	SCHEMBL1384680	0.83	KCNA5 (1.00)	KCNA5KCNH2MAT2ACYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.