SCHEMBL1385486

SCHEMBL1385486

CC1C(=O)N(Cc2ccc3c(N)cnnc3c2)CCN1CC=Cc1ccc(Cl)s1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1385484 1.00 F10 (0.32) F10
SCHEMBL4393690 0.88 F10 (0.35) F10
SCHEMBL1652219 0.88 F10 (0.35) F10
SCHEMBL4393695 0.88 F10 (0.35) F10
SCHEMBL4385646 0.88 F10 (0.35) F10
SCHEMBL1385929 0.85 F10 (0.33) F10
SCHEMBL1385923 0.85 F10 (0.33) F10
SCHEMBL1385926 0.85 F10 (0.33) F10
SCHEMBL4392806 0.84 F10 (0.47) F10
SCHEMBL1652586 0.84 F10 (0.47) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed