SCHEMBL13855063

SCHEMBL13855063

C[C@@H](NC(=O)COC(=O)Nc1cccc(C(=N)N)c1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 9/20 0.53
▸ F2 P00734 7/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ F10 P00742 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ PARP1 P09874 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13855064 1.00 F7 (0.53) F7F2L3MBTL1F10LMNA
SCHEMBL13855066 0.89 F7 (0.61) F7F2LMNAALDH1A1KDM4E
SCHEMBL13855067 0.89 F7 (0.61) F7F2LMNAALDH1A1KDM4E
SCHEMBL13855060 0.88 F7 (0.67) F7F2L3MBTL1F10
SCHEMBL13855061 0.88 F7 (0.67) F7F2L3MBTL1F10
SCHEMBL4225518 0.82 F7 (0.78) F7F2F10
SCHEMBL4225512 0.82 F7 (0.78) F7F2F10
SCHEMBL4231808 0.82 F7 (0.78) F7F2F10
SCHEMBL13855062 0.80 F7 (0.73) F7F2F10
SCHEMBL13855056 0.80 F7 (0.73) F7F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISH HEALTHCARE AG (CH) 2009-05-21 — — US disclosed
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations NOVO NORDISH HEALTHCARE AG (CH) 2009-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090130085-A1 Amidino-Compounds for Stabilizing Factor VII Polypeptide Formulations F7, F5, F8 F7 1/4885F2 9/4885L3MBTL1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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