Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385600 | 1.00 | F10 (0.51) | F10F2PRMT5WDR77F3 | |
| SCHEMBL1385551 | 0.94 | F10 (0.54) | F10F2PRMT5WDR77NAMPT | |
| SCHEMBL1385552 | 0.94 | F10 (0.54) | F10F2PRMT5WDR77NAMPT | |
| SCHEMBL1386737 | 0.87 | F10 (0.52) | F10F2PRMT5WDR77 | |
| SCHEMBL1385962 | 0.87 | F10 (0.52) | F10F2PRMT5WDR77NAMPT | |
| SCHEMBL1386136 | 0.87 | F10 (0.56) | F10F2PRMT5WDR77NAMPT | |
| SCHEMBL1385003 | 0.87 | F10 (0.50) | F10F2PRMT5WDR77 | |
| SCHEMBL1386675 | 0.87 | F10 (0.51) | F10F2PRMT5WDR77 | |
| SCHEMBL1386332 | 0.85 | F10 (0.54) | F10F2PRMT5WDR77NAMPT | |
| SCHEMBL1384672 | 0.82 | F10 (0.62) | F10F2PRMT5WDR77NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |