SCHEMBL138562

SCHEMBL138562

CCCCCCC#C[C](C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.48
HMGCR P04035 3/20 0.48
RECQL P46063 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
BLM P54132 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.40
THRB P10828 1/20 0.40
EPHX2 P34913 1/20 0.38
DNM1 Q05193 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141442 1.00 PTPN7 (0.48) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL135615 0.97 PTPN7 (0.45) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL7199135 0.90
SCHEMBL2973182 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2971217 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2971333 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2965662 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2975852 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2969743 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1
SCHEMBL2964415 0.84 PTPN7 (0.52) PTPN7HMGCRRECQLTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3223952-B1 ENERGY INPUT DURING AGGLOMERATION FOR MAGNETIC SEPARATION BASF SE (DE) 2024-01-17 EP disclosed
EP-4301520-A1 MAGNETIC SEPARATION OF PARTICLES SUPPORTED BY SPECIFIC SURFACTANTS BASF SE (DE) 2024-01-10 EP disclosed
CN-116438009-A Particle magnetic separation assisted by specific surfactants 巴斯夫欧洲公司 2023-07-14 CN disclosed
WO-2022184817-A1 MAGNETIC SEPARATION OF PARTICLES SUPPORTED BY SPECIFIC SURFACTANTS BASF SE (DE) 2022-09-09 WO disclosed
US-11110468-B2 Separation of a mixture using magnetic carrier particles BASF SE (DE) 2021-09-07 US disclosed
US-10807100-B2 Concentrate quality BASF SE (DE) 2020-10-20 US disclosed
US-10799881-B2 Energy input during agglomeration for magnetic separation BASF SE (DE) 2020-10-13 US disclosed
EP-3661652-A1 SEPARATION OF A MIXTURE USING MAGNETIC CARRIER PARTICLES BASF SE (DE) 2020-06-10 EP disclosed
US-20200122160-A1 SEPARATION OF A MIXTURE USING MAGNETIC CARRIER PARTICLES BASF SE (DE) 2020-04-23 US disclosed
US-10549287-B2 Ultraflotation with magnetically responsive carrier particles BASF SE (DE) 2020-02-04 US disclosed
US-20120058463-A1 HYDROPHOBIC, FUNCTIONALIZED PARTICLES SIEMENS AG (DE) 2012-03-08 US disclosed
EP-0389162-B1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES (JP) 1993-12-08 EP disclosed
EP-0274064-B1 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1992-03-18 EP disclosed
US-5086071-A Improved chemical stability and ppotent in vivo TORAY INDUSTRIES, INC. (JP) 1992-02-04 US disclosed
EP-0232776-B1 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1990-10-24 EP disclosed
EP-0389162-A1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1990-09-26 EP disclosed
US-4880939-A ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS TORAY INDUSTRIES (JP) 1989-11-14 US disclosed
US-4775692-A ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT TORAY INDUSTRIES, INC. (JP) 1988-10-04 US disclosed
EP-0274064-A2 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1988-07-13 EP disclosed
EP-0232776-A2 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1987-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058463-A1 HYDROPHOBIC, FUNCTIONALIZED PARTICLES CD44, CD40LG, EPCAM PTPN7 2791/4885HMGCR 2822/4885RECQL 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.