SCHEMBL1385690

SCHEMBL1385690

CCOC(=O)CC(C)(C)c1csc(CN2C(=O)CN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2COC)n1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1385688 1.00 F10 (0.46) F10
SCHEMBL1386564 0.87 F10 (0.49) F10
SCHEMBL1386567 0.87 F10 (0.49) F10
SCHEMBL27572597 0.86 F10 (0.34) F10
SCHEMBL1385462 0.84 F10 (0.53) F10
SCHEMBL1384706 0.83 F10 (0.53) F10
SCHEMBL1384704 0.83 F10 (0.53) F10
SCHEMBL1387014 0.83 F10 (0.49) F10
SCHEMBL7144387 0.79 F10 (0.51) F10
SCHEMBL1385894 0.78 F10 (0.45) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed