Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383888 | 0.91 | EDNRB (0.74) | EDNRBEDNRA | |
| SCHEMBL7699764 | 0.83 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL7699763 | 0.83 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL5764890 | 0.81 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL7701542 | 0.81 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7694089 | 0.81 | EDNRB (0.72) | EDNRBEDNRA | |
| SCHEMBL7694086 | 0.81 | EDNRB (0.72) | EDNRBEDNRA | |
| SCHEMBL7696657 | 0.81 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7696038 | 0.81 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7696041 | 0.81 | EDNRB (0.64) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4832706-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1309564-B1 | ARYLETHENE-SULFONAMIDES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-14 | — | — | EP | claimed |