Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GSDMD | P57764 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.40 |
| ▸ | PHGDH | O43175 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213880 | 0.97 | CA12 (0.43) | EHMT2EHMT1CA12CA1CA2 | |
| SCHEMBL27713781 | 0.95 | EHMT2 (0.42) | EHMT2EHMT1CA12CA1CA2 | |
| Water SCHEMBL11657597 | 0.95 | EHMT2 (0.42) | EHMT2EHMT1CA12CA1CA2 | |
| Water SCHEMBL165775 | 0.95 | EHMT2 (0.42) | EHMT2EHMT1CA12CA1CA2 | |
| Water SCHEMBL2996455 | 0.95 | EHMT2 (0.42) | EHMT2EHMT1CA12CA1CA2 | |
| SCHEMBL48383 | 0.95 | CA12 (0.46) | EHMT2EHMT1CA12CA1CA2 | |
| Alcohol SCHEMBL28178874 | 0.92 | EHMT2 (0.40) | EHMT2EHMT1CA12CA1CA2 | |
| Methyl Alcohol SCHEMBL27077116 | 0.92 | EHMT2 (0.40) | EHMT2EHMT1CA12CA1CA2 | |
| SCHEMBL25284943 | 0.92 | CA12 (0.43) | EHMT2EHMT1CA12CA1CA2 | |
| SCHEMBL1882185 | 0.92 | CA12 (0.43) | EHMT2EHMT1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129118-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H LEE MOFFITT CANCER CT & RES (US) | 2025-04-24 | — | — | US | disclosed |
| US-12173087-B2 | Melanocortin 1 receptor ligands and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-20230167154-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H LEE MOFFITT CANCER CT & RES (US) | 2023-06-01 | — | — | US | disclosed |
| US-11230568-B2 | Melanocortin 1 receptor ligands and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-10329326-B2 | Melanocortin 1 receptor ligands and methods of use | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2019-06-25 | — | — | US | disclosed |
| US-20170218017-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H LEE MOFFITT CANCER CT & RES (US) | 2017-08-03 | — | — | US | disclosed |
| US-9539301-B2 | Melanotropin ligands for skin care | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-01-10 | — | — | US | disclosed |
| US-9441013-B2 | Melanocortin 1 receptor ligands and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160175384-A1 | MELANOTROPIN LIGANDS FOR SKIN CARE | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2016-06-23 | — | — | US | disclosed |
| US-9290539-B2 | Melanotropin ligands for skin care | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150284431-A1 | MELANOTROPIN LIGANDS FOR SKIN CARE | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2015-10-08 | — | — | US | disclosed |
| US-20140112873-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2014-04-24 | — | — | US | disclosed |
| WO-2012158960-A2 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329326-B2 | Melanocortin 1 receptor ligands and methods of use | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
| US-20160175384-A1 | MELANOTROPIN LIGANDS FOR SKIN CARE | MC1R, MC3R, MC5R | EHMT2 2805/4885EHMT1 1279/4885CA12 4600/4885 |
| US-20170218017-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
| US-11230568-B2 | Melanocortin 1 receptor ligands and methods of use | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
| US-20140112873-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
| US-12173087-B2 | Melanocortin 1 receptor ligands and methods of use | MC1R, MC3R, MC5R | EHMT2 3575/4885EHMT1 2426/4885CA12 1039/4885 |
| US-20150284431-A1 | MELANOTROPIN LIGANDS FOR SKIN CARE | MC1R, MC3R, MC5R | EHMT2 2828/4885EHMT1 1548/4885CA12 4738/4885 |
| US-20230167154-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
| US-20250129118-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | MC1R, MC3R, MC5R | EHMT2 3537/4885EHMT1 2408/4885CA12 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.