Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392648 | 0.87 | F10 (0.66) | F10F2 | |
| SCHEMBL1653420 | 0.84 | F10 (0.53) | F10F2DRD3DRD2HRH4 | |
| SCHEMBL7408155 | 0.81 | F10 (0.51) | F10F2HRH4 | |
| SCHEMBL7408159 | 0.81 | F10 (0.51) | F10F2HRH4 | |
| SCHEMBL1385605 | 0.78 | F10 (0.56) | F10F2DRD4DRD3DRD2 | |
| SCHEMBL1654883 | 0.77 | DRD4 (0.47) | F10F2DRD4DRD3DRD2 | |
| SCHEMBL1653577 | 0.73 | F10 (0.77) | F10F2 | |
| SCHEMBL29941543 | 0.73 | HRH4 (0.46) | F10F2DRD4DRD3DRD2 | |
| SCHEMBL4387736 | 0.73 | F10 (0.67) | F10F2 | |
| SCHEMBL1384898 | 0.73 | F10 (1.00) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |