Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980420 | 0.80 | BACE1 (0.41) | BACE1CYP2D6 | |
| SCHEMBL13859218 | 0.78 | BACE1 (0.49) | BACE1CYP2D6 | |
| SCHEMBL1984301 | 0.77 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL13268451 | 0.74 | BACE1 (0.38) | BACE1 | |
| SCHEMBL13859156 | 0.74 | BACE1 (0.45) | BACE1 | |
| SCHEMBL13268504 | 0.74 | BACE1 (0.32) | BACE1CYP2D6 | |
| SCHEMBL14165303 | 0.74 | BACE2 (0.44) | BACE1 | |
| SCHEMBL1979221 | 0.74 | BACE2 (0.44) | BACE1 | |
| SCHEMBL13859149 | 0.73 | MAPK1 (0.33) | — | |
| SCHEMBL13859030 | 0.72 | SMN1; SMN2 (0.33) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709992-A1 | 1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012156284-A1 | 1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-22 | — | — | WO | disclosed |