Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11967494 | 0.93 | PIK3CA (0.70) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL1485319 | 0.89 | PIK3CA (0.69) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL1485457 | 0.89 | PIK3CA (0.69) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL15488254 | 0.88 | PIK3CA (0.69) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL12689262 | 0.88 | PIK3CA (0.67) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL1485585 | 0.87 | PIK3CA (0.70) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL1485736 | 0.87 | PIK3CA (0.69) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL12693041 | 0.87 | PIK3CA (0.69) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL11967508 | 0.87 | PIK3CA (0.75) | PIK3CAPIK3CGPIK3CD | |
| SCHEMBL18631858 | 0.86 | PIK3CA (0.68) | PIK3CAPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012156379-A1 | PIK3/P110α INHIBITORS FOR PREVENTION OF RESTENOSIS BY APPLICATION AS AN IMPLANT COATING | Universität Zürich (CH) | 2012-11-22 | — | — | WO | disclosed |