Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.68 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386118 | 1.00 | F10 (0.68) | F10F2PRMT5WDR77DAO | |
| SCHEMBL1384460 | 0.93 | F10 (0.60) | F10F2PRMT5WDR77DAO | |
| SCHEMBL4394248 | 0.93 | F10 (0.60) | F10F2PRMT5WDR77DAO | |
| SCHEMBL1653488 | 0.90 | F10 (0.71) | F10F2PRMT5WDR77 | |
| SCHEMBL4391729 | 0.90 | F10 (0.71) | F10F2PRMT5WDR77 | |
| SCHEMBL1386462 | 0.85 | F10 (0.68) | F10F2PRMT5WDR77DAO | |
| SCHEMBL1386464 | 0.85 | F10 (0.68) | F10F2PRMT5WDR77DAO | |
| SCHEMBL1385786 | 0.85 | F10 (0.58) | F10F2PRMT5WDR77HCRTR1 | |
| SCHEMBL1386999 | 0.83 | F10 (0.56) | F10F2PRMT5WDR77 | |
| SCHEMBL1386997 | 0.83 | F10 (0.56) | F10F2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4829449-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| JP-2003508353-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | claimed |
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |