SCHEMBL1386486

SCHEMBL1386486

Nc1cc(/C=C/C(=O)N2CCN(COCCc3ccc4c(N)ncnc4c3)C(=O)C2)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.39
GPR183 P32249 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1386228 0.94 F10 (0.39) F10GPR183
SCHEMBL1386784 0.89 F10 (0.40) F10GPR183
SCHEMBL4389071 0.89 F10 (0.49) F10GPR183
SCHEMBL1652237 0.89 F10 (0.49) F10GPR183
SCHEMBL1384276 0.88 F10 (0.39) F10
SCHEMBL4398522 0.85 F10 (0.37) F10GPR183
SCHEMBL4397531 0.85 F10 (0.37) F10
SCHEMBL4387285 0.82 F10 (0.44) F10
SCHEMBL1652859 0.80 F10 (0.55) F10GPR183
SCHEMBL4390236 0.80 F10 (0.55) F10GPR183

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829449-B2 2011-12-07 JP claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed